The present study was carried out to evaluate expression of matrix metalloproteinases in induced rat mammary\r\ntumours, based on real time PCR technique. In rats, tumours were induced by oral administration of DMBA. The most common\r\nhistological type of mammary tumour encountered in rats was papillary adenocarcinoma. The expression of MMP2 was\r\nobserved by PCR methods in all the tumour types of rat mammary tumours. The expression was higher in malignant tumours\r\ncompared to benign and non-neoplastic growths. Among malignant tumours the expression of MMP2 gene mRNA varied\r\nbetween the tumour types. In rat mammary tumours the MMP2 gene mRNA expressions were highest in papillary\r\nadenocarcinoma.
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